Articles | Volume 12, issue 1
https://doi.org/10.5194/ms-12-501-2021
https://doi.org/10.5194/ms-12-501-2021
Research article
 | 
18 May 2021
Research article |  | 18 May 2021

Structure optimization of a pipetting device to improve the insertion effect of tips

Zeng Huang, Chenxue Wang, Qian Su, and Zhiping Lian

Related subject area

Subject: Machining and Manufacturing Processes | Techniques and Approaches: Mathematical Modeling and Analysis
Comparison of finite element analysis results with strain gauge measurements of a front axle housing
Yılmaz Gür and Gökhan Cen
Mech. Sci., 15, 257–268, https://doi.org/10.5194/ms-15-257-2024,https://doi.org/10.5194/ms-15-257-2024, 2024
Short summary
Study on a grinding force model of a variable grinding contact area during knife-edge surface grinding
Baohua Yu, Tianfeng Lou, Dongwei Chen, Jie Rui, Wenliang Li, and Yuepeng Chen
Mech. Sci., 14, 531–543, https://doi.org/10.5194/ms-14-531-2023,https://doi.org/10.5194/ms-14-531-2023, 2023
Short summary
Finite-element method for the analysis of surface stress concentration factor and relative stress gradient for machined surfaces
Guangtao Xu, Zeyuan Qiao, Shaokang Wu, Tianyi Liu, Minghao Zhao, and Gang Wang
Mech. Sci., 14, 451–461, https://doi.org/10.5194/ms-14-451-2023,https://doi.org/10.5194/ms-14-451-2023, 2023
Short summary
Roundness error evaluation in image domain based on an improved bee colony algorithm
Benchi Jiang, Xin Du, Shilei Bian, and Lulu Wu
Mech. Sci., 13, 577–584, https://doi.org/10.5194/ms-13-577-2022,https://doi.org/10.5194/ms-13-577-2022, 2022
Short summary
Analytical model establishment and attitude calculation of a parallel leaf-spring carrying mechanism
Peng Li, Zheng-Rong Tong, and Wei-Hua Zhang
Mech. Sci., 13, 311–320, https://doi.org/10.5194/ms-13-311-2022,https://doi.org/10.5194/ms-13-311-2022, 2022
Short summary

Cited articles

Allison, J., Bailey, D, M., Johnnie, W., and Mikesell, B.: An automatic micropipette fluid dispenser, Behav. Res. Meth. Ins. C., 22, 517–519, https://doi.org/10.3758/BF03204435, 1990. 
Chen, Z., Fang, Y., and Peng, J.: Design and Implementation of Temperature Acquisition System for Polymerase Chain Reaction, Journal of Bionanoscience, 9, 480–483, https://doi.org/10.1166/jbns.2015.1334, 2015. 
Dutka, F., Opalski, A, S., and Garstecki, P.: Nano-liter droplet libraries from a pipette: step emulsificator that stabilizes droplet volume against variation in flow rate, Lab Chip., 16, 2044–2049, https://doi.org/10.1039/c6lc00265j, 2016. 
Engström, K. and Meiselman, H. J.: Fabrication of glass micropipettes: A semi-automatic approach for trimming the pipette tip, Biorheology, 29, 499–506, https://doi.org/10.1016/j.biomaterials.2012.08.045, 1992. 
He, J.: Integration of Laboratory Automation Analyzer and Information System, China Digital Medicine., 06, 99–102, https://doi.org/10.3969/j.issn.1673-7571.2011.08.031, 2011. 
Download
Short summary
In this paper, a high-rigidity screw-type tip-inserting mechanism with a good centering effect is designed. The structural characteristics and working principle of the inserting mechanism are introduced, the stiffness model of the new-type pipetting device is established and its stiffness and axial deformation are calculated. Finally, a multi-station high-throughput automatic pipette produced by a company was used as an example to optimize and improve it and conduct a prototype test.