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  <front>
    <journal-meta><journal-id journal-id-type="publisher">MS</journal-id><journal-title-group>
    <journal-title>Mechanical Sciences</journal-title>
    <abbrev-journal-title abbrev-type="publisher">MS</abbrev-journal-title><abbrev-journal-title abbrev-type="nlm-ta">Mech. Sci.</abbrev-journal-title>
  </journal-title-group><issn pub-type="epub">2191-916X</issn><publisher>
    <publisher-name>Copernicus Publications</publisher-name>
    <publisher-loc>Göttingen, Germany</publisher-loc>
  </publisher></journal-meta>
    <article-meta>
      <article-id pub-id-type="doi">10.5194/ms-13-387-2022</article-id><title-group><article-title>A passive upper-limb exoskeleton for industrial application based on
pneumatic artificial muscles</article-title><alt-title>A passive upper-limb exoskeleton for industrial application</alt-title>
      </title-group><?xmltex \runningtitle{A passive upper-limb exoskeleton for industrial application}?><?xmltex \runningauthor{M.~Paterna et al.}?>
      <contrib-group>
        <contrib contrib-type="author" corresp="no" rid="aff1">
          <name><surname>Paterna</surname><given-names>Maria</given-names></name>
          
        </contrib>
        <contrib contrib-type="author" corresp="no" rid="aff1">
          <name><surname>Magnetti Gisolo</surname><given-names>Stefania</given-names></name>
          
        </contrib>
        <contrib contrib-type="author" corresp="yes" rid="aff1">
          <name><surname>De Benedictis</surname><given-names>Carlo</given-names></name>
          <email>carlo.debenedictis@polito.it</email>
        <ext-link>https://orcid.org/0000-0003-0687-0739</ext-link></contrib>
        <contrib contrib-type="author" corresp="no" rid="aff2">
          <name><surname>Muscolo</surname><given-names>Giovanni Gerardo</given-names></name>
          
        </contrib>
        <contrib contrib-type="author" corresp="no" rid="aff1">
          <name><surname>Ferraresi</surname><given-names>Carlo</given-names></name>
          
        </contrib>
        <aff id="aff1"><label>1</label><institution>Department of Mechanical and Aerospace Engineering, Politecnico di
Torino, Turin, 10129, Italy</institution>
        </aff>
        <aff id="aff2"><label>2</label><institution>Department of Computer Science, University of Verona, Verona, 37134,
Italy</institution>
        </aff>
      </contrib-group>
      <author-notes><corresp id="corr1">Carlo De Benedictis (carlo.debenedictis@polito.it)</corresp></author-notes><pub-date><day>27</day><month>April</month><year>2022</year></pub-date>
      
      <volume>13</volume>
      <issue>1</issue>
      <fpage>387</fpage><lpage>398</lpage>
      <history>
        <date date-type="received"><day>15</day><month>December</month><year>2021</year></date>
           <date date-type="rev-recd"><day>30</day><month>March</month><year>2022</year></date>
           <date date-type="accepted"><day>1</day><month>April</month><year>2022</year></date>
      </history>
      <permissions>
        <copyright-statement>Copyright: © 2022 Maria Paterna et al.</copyright-statement>
        <copyright-year>2022</copyright-year>
      <license license-type="open-access"><license-p>This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this licence, visit <ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by/4.0/">https://creativecommons.org/licenses/by/4.0/</ext-link></license-p></license></permissions><self-uri xlink:href="https://ms.copernicus.org/articles/13/387/2022/ms-13-387-2022.html">This article is available from https://ms.copernicus.org/articles/13/387/2022/ms-13-387-2022.html</self-uri><self-uri xlink:href="https://ms.copernicus.org/articles/13/387/2022/ms-13-387-2022.pdf">The full text article is available as a PDF file from https://ms.copernicus.org/articles/13/387/2022/ms-13-387-2022.pdf</self-uri>
      <abstract><title>Abstract</title>

      <p id="d1e121">In recent years, exoskeletons are increasingly spreading
into the industrial manufacturing sector to improve productivity and to
reduce the incidence of work-related musculoskeletal diseases. The aim of
this paper is to present a 2 degrees of freedom (DoF) passive upper-limb
exoskeleton, consisting of two McKibben pneumatic artificial muscles (PAMs),
and used for assisting workers during activities that require them to keep
their hands in a sustained position over the head for a long time.</p>

      <p id="d1e124">Simulations are performed to test two different commercial PAMs and two
different designs of the transmission system used to convey the traction
force exerted by the pneumatic muscles to the limb; then the results are
discussed. A preliminary assembly of the exoskeleton is also presented. The
study confirms that PAMs can be used to realize a passive upper-limb
exoskeleton for industrial application and that appropriate working space
can be obtained with an accurate design of the transmission system.</p>
  </abstract>
    </article-meta>
  </front>
<body>
      

<sec id="Ch1.S1" sec-type="intro">
  <label>1</label><title>Introduction</title>
      <p id="d1e136">Work-related diseases reduce the quality of life of workers and entail high
costs for enterprises and society. Moreover, they represent an increasingly
concerning issue due to their high incidence. In Europe, three in five
workers suffer from work-related diseases, which, in 60 % of cases,
consists of musculoskeletal diseases (MSDs). Finally, 40 % of these diseases
concern the upper limbs and shoulders. A risk factor is represented by those
activities requiring the workers to keep their hands in a sustained position
over the head for a long time. The large moments due to the gravitational
forces involved make the compressive load acting on the shoulder equal to
about 50 % of the total body weight, thus increasing the possibility of
developing degenerative tendinitis of biceps and supraspinatus
(Hall, 2011; Sylla et
al., 2014).</p>
      <p id="d1e139">In recent years, the use of robots has increased in all industrial sectors
to overcome the natural limitations of humans in performing repetitive and
heavy tasks. However, manufacturing automation is limited by frequent
variations in the production systems and by the increasing need for
customization and personalization of the products. An alternative could be
represented by the use of exoskeletons, which can be worn by workers to
increase their performance and strength and to reduce the load on the
shoulder  (Gopura and Kiguchi, 2009) and hence the
incidence of MSDs. Industrial upper-limb exoskeletons can be active or
passive. In the first case, they actively assist human movements thanks to
one or more actuators and an external power source
(Bai
et al., 2017; Ebrahimi, 2017; Mauri et al., 2019; Otten et al., 2018;
Stadler et al., 2016). The actuators are usually placed on the back of the
user, whereas the transmission system can be constituted of cables and
hidden pulleys or gears. Passive exoskeletons, instead, return the
previously stored energy through passive elements
(Altenburger
et al., 2016; Angold et al., 2017; Doyle, 2013; Kim et al., 2018; Maurice et
al., 2020; Moisè et al., 2019; Pacifico et al., 2020; Spada et al.,
2017; de Vries et al., 2019; Wang et al., 2021); hence, they do not require
an external power source to supply and control the actuation system. In
particular, they often employ spring-based systems (e.g., passive
parallelogram or cantilever–spring, gear–spring, cam–spring, pulley–spring, or cable–spring mechanisms) to
balance the gravitational forces. The design of both active and passive
exoskeletons must take into account that the device should be easily and
quickly worn, as well as easily adaptable to the anthropometric
characteristics of different subjects. Moreover, the exoskeleton joints
should be aligned with the anatomical joints of the worker's upper limbs to
avoid undesired forces that may cause pain, dislocation, or fracture
(Cui et al.,
2017; Dehez and Sapin, 2011; Lo and Xie, 2012; Park et al., 2008). However,
passive exoskeletons are lighter and less bulky than active exoskeletons. In
addition, they have a higher power-to-weight ratio and higher autonomy;
hence, they are more suitable than active exoskeletons for industrial
applications.</p>
      <p id="d1e142">Thanks to their intrinsic deformability, high power-to-weight ratio, and
similarity to human muscles, pneumatic artificial muscles (PAMs) have been
employed to develop active exoskeletons for medical rehabilitation
(Balasubramanian
et al., 2008; Klein et al., 2008; Tsagarakis and Caldwell, 2003). However,
the heaviness and bulkiness related to the pressurized air supply limit the
use of pneumatic-actuated active exoskeletons to fixed-platform-based
systems (Gull et al., 2020). Given their passive
characteristics when inflated with pressurized air, PAMs can also be
employed as passive elements within the structure of an exoskeleton,
similarly to spring-based systems
(Magnetti Gisolo et al., 2021; Lo
Piccolo, et al., 2022; Pardoel and Doumit, 2019). In this way, it is
possible to take advantage of the aforementioned characteristics of PAMs,
which naturally fit any application based on the interaction of an external
device (that is, the exoskeleton) and a human being (i.e., a human-machine
interface), without a critical increase in the bulkiness and weight of the
overall system. The availability of PAMs with different sizes,
characteristics, and load capabilities, as well as the possibility to
regulate the internal pressure to achieve different behaviors, allow for
extensive customization of the actuator's response that can match different
applications and working conditions. With respect to simpler elastic
elements, the main drawbacks of this technology are the nonlinear behavior
and the reduced stroke, which can be improved by an appropriate design of
the transmission system. This paper aims to describe a 2 degrees of freedom
(DoF) passive upper-limb exoskeleton, based on two McKibben PAMs, for
assisting workers during a long-lasting overhead task. A preliminary
feasibility study of this system has been presented in a previous work
(Magnetti Gisolo et al., 2021), of which the current
paper represents an extended version. A design of the exoskeleton is
described, respectful of the biomechanical aspects, and the feasibility of
the proposed solution in a larger workspace is verified. The choice of the
PAM, the design of the transmission system, and the full architecture of the
exoskeleton are here presented and discussed, to demonstrate the feasibility
of the solution proposed.</p>
</sec>
<sec id="Ch1.S2">
  <label>2</label><title>Materials and methods</title>
<sec id="Ch1.S2.SS1">
  <label>2.1</label><title>Design specifications and selection of PAMs</title>
      <p id="d1e160">The overall objective of this study is to design a passive upper-limb
exoskeleton to assist the worker during an overhead task. The shoulder
torque generated by the arm weight depends on both the subject anthropometry
and the rotations at the elbow and shoulder joints. The shoulder torque
reaches its maximum value when the shoulder elevation angle <inline-formula><mml:math id="M1" display="inline"><mml:mrow><mml:msub><mml:mi mathvariant="italic">θ</mml:mi><mml:mn mathvariant="normal">1</mml:mn></mml:msub></mml:mrow></mml:math></inline-formula>
and the elbow flexion–extension angle <inline-formula><mml:math id="M2" display="inline"><mml:mrow><mml:msub><mml:mi mathvariant="italic">θ</mml:mi><mml:mn mathvariant="normal">2</mml:mn></mml:msub></mml:mrow></mml:math></inline-formula> are, respectively,
90  and 0<inline-formula><mml:math id="M3" display="inline"><mml:msup><mml:mi/><mml:mo>∘</mml:mo></mml:msup></mml:math></inline-formula>. The pattern of the gravitational torque due
to the weight of the upper limb alone, shown in Fig. 1, is calculated thanks
to the inertial parameters identified by Zatsiorsky (de Leva, 1996) and
listed in Table 1 for a subject of 1.74 m height and body mass equal to 73 kg.</p>

      <?xmltex \floatpos{t}?><fig id="Ch1.F1" specific-use="star"><?xmltex \currentcnt{1}?><?xmltex \def\figurename{Figure}?><label>Figure 1</label><caption><p id="d1e196">Torque due to gravity with respect to the elevation angle of the
upper arm <inline-formula><mml:math id="M4" display="inline"><mml:mrow><mml:msub><mml:mi mathvariant="italic">θ</mml:mi><mml:mn mathvariant="normal">1</mml:mn></mml:msub></mml:mrow></mml:math></inline-formula> and the forearm flexion angle <inline-formula><mml:math id="M5" display="inline"><mml:mrow><mml:msub><mml:mi mathvariant="italic">θ</mml:mi><mml:mn mathvariant="normal">2</mml:mn></mml:msub></mml:mrow></mml:math></inline-formula>. SJ
and EJ represent the glenohumeral (shoulder) joint center and the elbow
joint center, respectively, whereas CoM<inline-formula><mml:math id="M6" display="inline"><mml:msub><mml:mi/><mml:mn mathvariant="normal">1</mml:mn></mml:msub></mml:math></inline-formula>, CoM<inline-formula><mml:math id="M7" display="inline"><mml:msub><mml:mi/><mml:mn mathvariant="normal">2</mml:mn></mml:msub></mml:math></inline-formula>, and CoM<inline-formula><mml:math id="M8" display="inline"><mml:msub><mml:mi/><mml:mn mathvariant="normal">3</mml:mn></mml:msub></mml:math></inline-formula> are
the centers of mass of upper arm, forearm, and hand.</p></caption>
          <?xmltex \igopts{width=398.338583pt}?><graphic xlink:href="https://ms.copernicus.org/articles/13/387/2022/ms-13-387-2022-f01.png"/>

        </fig>

<?xmltex \floatpos{t}?><table-wrap id="Ch1.T1"><?xmltex \currentcnt{1}?><label>Table 1</label><caption><p id="d1e257">Anthropometric data used to estimate joint torque values in Fig. 1. SJ and EJ represent the glenohumeral (shoulder) joint center and the elbow
joint center, respectively, whereas CoM is the center of mass of each
segment.</p></caption><oasis:table frame="topbot"><oasis:tgroup cols="2">
     <oasis:colspec colnum="1" colname="col1" align="left"/>
     <oasis:colspec colnum="2" colname="col2" align="left"/>
     <oasis:thead>
       <oasis:row rowsep="1">
         <oasis:entry colname="col1">Measurement</oasis:entry>
         <oasis:entry colname="col2">Value</oasis:entry>
       </oasis:row>
     </oasis:thead>
     <oasis:tbody>
       <oasis:row>
         <oasis:entry colname="col1">Upper arm weight</oasis:entry>
         <oasis:entry colname="col2">1.98 kg</oasis:entry>
       </oasis:row>
       <oasis:row>
         <oasis:entry colname="col1">Forearm weight</oasis:entry>
         <oasis:entry colname="col2">1.18 kg</oasis:entry>
       </oasis:row>
       <oasis:row>
         <oasis:entry colname="col1">Hand weight</oasis:entry>
         <oasis:entry colname="col2">0.44 kg</oasis:entry>
       </oasis:row>
       <oasis:row>
         <oasis:entry colname="col1">SJ–upper-arm CoM distance</oasis:entry>
         <oasis:entry colname="col2">0.16 m</oasis:entry>
       </oasis:row>
       <oasis:row>
         <oasis:entry colname="col1">EJ–forearm CoM distance</oasis:entry>
         <oasis:entry colname="col2">0.12 m</oasis:entry>
       </oasis:row>
       <oasis:row>
         <oasis:entry colname="col1">EJ–hand CoM distance</oasis:entry>
         <oasis:entry colname="col2">0.34 m</oasis:entry>
       </oasis:row>
     </oasis:tbody>
   </oasis:tgroup></oasis:table></table-wrap>

      <p id="d1e340">To define the size of the pneumatic muscle and the architecture of the
transmission system, the heaviest exoskeleton working condition is
considered. Therefore, the system behavior is studied by changing the
shoulder elevation angle (<inline-formula><mml:math id="M9" display="inline"><mml:mrow><mml:msub><mml:mi mathvariant="italic">θ</mml:mi><mml:mn mathvariant="normal">1</mml:mn></mml:msub><mml:mo>∈</mml:mo></mml:mrow></mml:math></inline-formula> [90<inline-formula><mml:math id="M10" display="inline"><mml:msup><mml:mi/><mml:mo>∘</mml:mo></mml:msup></mml:math></inline-formula>, 120<inline-formula><mml:math id="M11" display="inline"><mml:msup><mml:mi/><mml:mo>∘</mml:mo></mml:msup></mml:math></inline-formula>]) while maintaining the elbow extended (<inline-formula><mml:math id="M12" display="inline"><mml:mrow><mml:msub><mml:mi mathvariant="italic">θ</mml:mi><mml:mn mathvariant="normal">2</mml:mn></mml:msub><mml:mo>=</mml:mo><mml:mn mathvariant="normal">0</mml:mn><mml:msup><mml:mi/><mml:mo>∘</mml:mo></mml:msup></mml:mrow></mml:math></inline-formula>).</p>
      <p id="d1e393">The tension force <inline-formula><mml:math id="M13" display="inline"><mml:mrow><mml:msub><mml:mi>F</mml:mi><mml:mi mathvariant="normal">mu</mml:mi></mml:msub></mml:mrow></mml:math></inline-formula> produced by a PAM is a function of many
parameters, such as supply pressure <inline-formula><mml:math id="M14" display="inline"><mml:mi>p</mml:mi></mml:math></inline-formula>, diameter, and percentage of muscle
contraction <inline-formula><mml:math id="M15" display="inline"><mml:mi>k</mml:mi></mml:math></inline-formula>. Therefore, two different sizes of the commercial McKibben
artificial muscles (DMSP series, nominal length <inline-formula><mml:math id="M16" display="inline"><mml:mrow><mml:msub><mml:mi>l</mml:mi><mml:mn mathvariant="normal">0</mml:mn></mml:msub><mml:mo>=</mml:mo><mml:mn mathvariant="normal">0.21</mml:mn></mml:mrow></mml:math></inline-formula> m, FESTO,
Germany) have been considered and tested for this application. The static
characteristics of the PAMs tension force, shown in Fig. 2, are provided by
the manufacturer and can be approximated by the modified Hill's muscle model
proposed by Pitei and Tóthová (2016) and described
by Eq. (1). The coefficients of the latter are obtained by interpolation and
listed in Table 2.
            <disp-formula id="Ch1.E1" content-type="numbered"><label>1</label><mml:math id="M17" display="block"><mml:mrow><mml:msub><mml:mi>F</mml:mi><mml:mi mathvariant="normal">mu</mml:mi></mml:msub><mml:mo>=</mml:mo><mml:mfenced close=")" open="("><mml:mrow><mml:msub><mml:mi>a</mml:mi><mml:mn mathvariant="normal">1</mml:mn></mml:msub><mml:mi>p</mml:mi><mml:mo>+</mml:mo><mml:msub><mml:mi>a</mml:mi><mml:mn mathvariant="normal">2</mml:mn></mml:msub></mml:mrow></mml:mfenced><mml:msup><mml:mi>e</mml:mi><mml:mrow><mml:msub><mml:mi>a</mml:mi><mml:mn mathvariant="normal">3</mml:mn></mml:msub><mml:mi>k</mml:mi></mml:mrow></mml:msup><mml:mo>+</mml:mo><mml:msub><mml:mi>a</mml:mi><mml:mn mathvariant="normal">4</mml:mn></mml:msub><mml:mi>k</mml:mi><mml:mi>p</mml:mi><mml:mo>+</mml:mo><mml:msub><mml:mi>a</mml:mi><mml:mn mathvariant="normal">5</mml:mn></mml:msub><mml:mi>p</mml:mi><mml:mo>+</mml:mo><mml:msub><mml:mi>a</mml:mi><mml:mn mathvariant="normal">6</mml:mn></mml:msub></mml:mrow></mml:math></disp-formula></p>

      <?xmltex \floatpos{t}?><fig id="Ch1.F2" specific-use="star"><?xmltex \currentcnt{2}?><?xmltex \def\figurename{Figure}?><label>Figure 2</label><caption><p id="d1e505">Static characteristics of McKibben muscles: DMSP-10-100N series
<bold>(a)</bold> and DMSP-20-200N series <bold>(b)</bold> from FESTO at different supply
pressures.</p></caption>
          <?xmltex \igopts{width=503.61378pt}?><graphic xlink:href="https://ms.copernicus.org/articles/13/387/2022/ms-13-387-2022-f02.png"/>

        </fig>

      <p id="d1e520">The choice of the PAM is mainly driven by the maximum force required by the
application as well as the desired shape of the force–contraction
characteristic, which also depends on the size and the bulkiness of the
actuator. However, PAMs generally have limited stroke; therefore, they
require appropriate transmission systems to achieve a wide workspace.
Moreover, the transmission system has a critical impact on the general
performance of the device. Indeed, to perform in the desired way, the
exoskeleton should exert a supporting torque as close as possible to the
torque due to the gravitational load. This result cannot be achieved by the
PAM itself; therefore, a transmission system able to adapt the
characteristics of the McKibben muscle to the external load is necessary. To
fulfill this requirement, two designs of the transmission system are
evaluated, aiming at reducing the mismatch between the torque provided by
the PAM and the gravitational torque throughout the range considered. In
both cases, the pneumatic muscles are placed behind the back of the user,
and the traction force is transmitted by the sliding of a tendon cable on a
pulley (first case, Fig. 3a) or on a fixed cam centered at the
glenohumeral joint (second case, Fig. 3b).</p>

      <?xmltex \floatpos{t}?><fig id="Ch1.F3" specific-use="star"><?xmltex \currentcnt{3}?><?xmltex \def\figurename{Figure}?><label>Figure 3</label><caption><p id="d1e525">Different designs of the exoskeleton: pulley-based design <bold>(a)</bold> and
cam-based design <bold>(b)</bold>.</p></caption>
          <?xmltex \igopts{width=503.61378pt}?><graphic xlink:href="https://ms.copernicus.org/articles/13/387/2022/ms-13-387-2022-f03.png"/>

        </fig>

<?xmltex \floatpos{t}?><table-wrap id="Ch1.T2"><?xmltex \currentcnt{2}?><label>Table 2</label><caption><p id="d1e544">Coefficients of Eq. (1) for approximating the static
characteristics of commercial FESTO McKibben muscles.</p></caption><oasis:table frame="topbot"><oasis:tgroup cols="3">
     <oasis:colspec colnum="1" colname="col1" align="left"/>
     <oasis:colspec colnum="2" colname="col2" align="right"/>
     <oasis:colspec colnum="3" colname="col3" align="right"/>
     <oasis:thead>
       <oasis:row rowsep="1">
         <oasis:entry colname="col1"/>
         <oasis:entry colname="col2">DMSP-10-100N</oasis:entry>
         <oasis:entry colname="col3">DMSP-20-200N</oasis:entry>
       </oasis:row>
     </oasis:thead>
     <oasis:tbody>
       <oasis:row>
         <oasis:entry colname="col1"><inline-formula><mml:math id="M18" display="inline"><mml:mrow><mml:msub><mml:mi>a</mml:mi><mml:mn mathvariant="normal">1</mml:mn></mml:msub></mml:mrow></mml:math></inline-formula></oasis:entry>
         <oasis:entry colname="col2">0.01584</oasis:entry>
         <oasis:entry colname="col3">0.0524</oasis:entry>
       </oasis:row>
       <oasis:row>
         <oasis:entry colname="col1"><inline-formula><mml:math id="M19" display="inline"><mml:mrow><mml:msub><mml:mi>a</mml:mi><mml:mn mathvariant="normal">2</mml:mn></mml:msub></mml:mrow></mml:math></inline-formula></oasis:entry>
         <oasis:entry colname="col2">130.8</oasis:entry>
         <oasis:entry colname="col3">257.6</oasis:entry>
       </oasis:row>
       <oasis:row>
         <oasis:entry colname="col1"><inline-formula><mml:math id="M20" display="inline"><mml:mrow><mml:msub><mml:mi>a</mml:mi><mml:mn mathvariant="normal">3</mml:mn></mml:msub></mml:mrow></mml:math></inline-formula></oasis:entry>
         <oasis:entry colname="col2"><inline-formula><mml:math id="M21" display="inline"><mml:mo>-</mml:mo></mml:math></inline-formula>0.3972</oasis:entry>
         <oasis:entry colname="col3"><inline-formula><mml:math id="M22" display="inline"><mml:mo>-</mml:mo></mml:math></inline-formula>0.3758</oasis:entry>
       </oasis:row>
       <oasis:row>
         <oasis:entry colname="col1"><inline-formula><mml:math id="M23" display="inline"><mml:mrow><mml:msub><mml:mi>a</mml:mi><mml:mn mathvariant="normal">4</mml:mn></mml:msub></mml:mrow></mml:math></inline-formula></oasis:entry>
         <oasis:entry colname="col2"><inline-formula><mml:math id="M24" display="inline"><mml:mo>-</mml:mo></mml:math></inline-formula>0.02605</oasis:entry>
         <oasis:entry colname="col3"><inline-formula><mml:math id="M25" display="inline"><mml:mo>-</mml:mo></mml:math></inline-formula>0.08369</oasis:entry>
       </oasis:row>
       <oasis:row>
         <oasis:entry colname="col1"><inline-formula><mml:math id="M26" display="inline"><mml:mrow><mml:msub><mml:mi>a</mml:mi><mml:mn mathvariant="normal">5</mml:mn></mml:msub></mml:mrow></mml:math></inline-formula></oasis:entry>
         <oasis:entry colname="col2">0.7911</oasis:entry>
         <oasis:entry colname="col3">2.583</oasis:entry>
       </oasis:row>
       <oasis:row>
         <oasis:entry colname="col1"><inline-formula><mml:math id="M27" display="inline"><mml:mrow><mml:msub><mml:mi>a</mml:mi><mml:mn mathvariant="normal">6</mml:mn></mml:msub></mml:mrow></mml:math></inline-formula></oasis:entry>
         <oasis:entry colname="col2"><inline-formula><mml:math id="M28" display="inline"><mml:mo>-</mml:mo></mml:math></inline-formula>127.1</oasis:entry>
         <oasis:entry colname="col3"><inline-formula><mml:math id="M29" display="inline"><mml:mo>-</mml:mo></mml:math></inline-formula>242.6</oasis:entry>
       </oasis:row>
     </oasis:tbody>
   </oasis:tgroup></oasis:table></table-wrap>

</sec>
<sec id="Ch1.S2.SS2">
  <label>2.2</label><title>A preliminary design of the transmission system based on pulley and cable</title>
      <p id="d1e746">In the first case (named pulley-based design), a transmission based on cable
and pulley (or a fixed passing point) is hypothesized to transmit the PAM
tension force to the bracelet, located on the user's upper arm (Lo Piccolo
et al., 2022). Concerning Fig. 3a, <inline-formula><mml:math id="M30" display="inline"><mml:mi>a</mml:mi></mml:math></inline-formula>, <inline-formula><mml:math id="M31" display="inline"><mml:mrow><mml:msub><mml:mi>c</mml:mi><mml:mn mathvariant="normal">0</mml:mn></mml:msub></mml:mrow></mml:math></inline-formula>, <inline-formula><mml:math id="M32" display="inline"><mml:mi mathvariant="italic">α</mml:mi></mml:math></inline-formula>, and
<inline-formula><mml:math id="M33" display="inline"><mml:mi mathvariant="italic">β</mml:mi></mml:math></inline-formula> are constant and define the size of the exoskeleton. The cable
length <inline-formula><mml:math id="M34" display="inline"><mml:mi>b</mml:mi></mml:math></inline-formula> and the lever arm <inline-formula><mml:math id="M35" display="inline"><mml:mi>r</mml:mi></mml:math></inline-formula> of the tension force, instead, depended on the
shoulder elevation angle <inline-formula><mml:math id="M36" display="inline"><mml:mrow><mml:msub><mml:mi mathvariant="italic">θ</mml:mi><mml:mn mathvariant="normal">1</mml:mn></mml:msub></mml:mrow></mml:math></inline-formula> and were calculated by the geometry
through Eqs. (2) and (3) (Magnetti Gisolo et al., 2021;
Lo Piccolo et al., 2022).

                <disp-formula specific-use="gather" content-type="numbered"><mml:math id="M37" display="block"><mml:mtable displaystyle="true"><mml:mlabeledtr id="Ch1.E2"><mml:mtd><mml:mtext>2</mml:mtext></mml:mtd><mml:mtd><mml:mrow><mml:mstyle class="stylechange" displaystyle="true"/><mml:mi>c</mml:mi><mml:mo>=</mml:mo><mml:msub><mml:mi>c</mml:mi><mml:mn mathvariant="normal">0</mml:mn></mml:msub><mml:mo>/</mml:mo><mml:mi>cos⁡</mml:mi><mml:mi mathvariant="italic">β</mml:mi><mml:mo>,</mml:mo><mml:mspace width="1em" linebreak="nobreak"/><mml:mi>b</mml:mi><mml:mo>=</mml:mo><mml:msqrt><mml:mrow><mml:msup><mml:mi>a</mml:mi><mml:mn mathvariant="normal">2</mml:mn></mml:msup><mml:mo>+</mml:mo><mml:msup><mml:mi>c</mml:mi><mml:mn mathvariant="normal">2</mml:mn></mml:msup><mml:mo>+</mml:mo><mml:mn mathvariant="normal">2</mml:mn><mml:mi>a</mml:mi><mml:mi>c</mml:mi><mml:mi>cos⁡</mml:mi><mml:mfenced close=")" open="("><mml:mrow><mml:msub><mml:mi mathvariant="italic">θ</mml:mi><mml:mn mathvariant="normal">1</mml:mn></mml:msub><mml:mo>+</mml:mo><mml:mi mathvariant="italic">β</mml:mi><mml:mo>-</mml:mo><mml:mi mathvariant="italic">α</mml:mi></mml:mrow></mml:mfenced></mml:mrow></mml:msqrt><mml:mo>;</mml:mo></mml:mrow></mml:mtd></mml:mlabeledtr><mml:mlabeledtr id="Ch1.E3"><mml:mtd><mml:mtext>3</mml:mtext></mml:mtd><mml:mtd><mml:mrow><mml:mstyle class="stylechange" displaystyle="true"/><mml:mtable rowspacing="0.2ex" class="split" displaystyle="true" columnalign="right left"><mml:mtr><mml:mtd/><mml:mtd><mml:mrow><mml:mi>S</mml:mi><mml:mo>=</mml:mo><mml:mfenced close=")" open="("><mml:mrow><mml:mi>a</mml:mi><mml:mo>+</mml:mo><mml:mi>b</mml:mi><mml:mo>+</mml:mo><mml:mi>c</mml:mi></mml:mrow></mml:mfenced><mml:mo>/</mml:mo><mml:mn mathvariant="normal">2</mml:mn><mml:mo>,</mml:mo><mml:mspace linebreak="nobreak" width="1em"/><mml:mi>A</mml:mi><mml:mo>=</mml:mo><mml:msqrt><mml:mrow><mml:mi>S</mml:mi><mml:mfenced open="(" close=")"><mml:mrow><mml:mi>S</mml:mi><mml:mo>-</mml:mo><mml:mi>a</mml:mi></mml:mrow></mml:mfenced><mml:mfenced close=")" open="("><mml:mrow><mml:mi>S</mml:mi><mml:mo>-</mml:mo><mml:mi>b</mml:mi></mml:mrow></mml:mfenced><mml:mfenced close=")" open="("><mml:mrow><mml:mi>S</mml:mi><mml:mo>-</mml:mo><mml:mi>c</mml:mi></mml:mrow></mml:mfenced></mml:mrow></mml:msqrt></mml:mrow></mml:mtd></mml:mtr><mml:mtr><mml:mtd/><mml:mtd><mml:mrow><mml:mi>r</mml:mi><mml:mo>=</mml:mo><mml:mn mathvariant="normal">2</mml:mn><mml:mi>A</mml:mi><mml:mo>/</mml:mo><mml:mi>b</mml:mi><mml:mo>.</mml:mo></mml:mrow></mml:mtd></mml:mtr></mml:mtable></mml:mrow></mml:mtd></mml:mlabeledtr></mml:mtable></mml:math></disp-formula>

            In the equations, <inline-formula><mml:math id="M38" display="inline"><mml:mi>A</mml:mi></mml:math></inline-formula> is the area of the triangle (<inline-formula><mml:math id="M39" display="inline"><mml:mi>a</mml:mi></mml:math></inline-formula>, <inline-formula><mml:math id="M40" display="inline"><mml:mi>b</mml:mi></mml:math></inline-formula>, <inline-formula><mml:math id="M41" display="inline"><mml:mi>c</mml:mi></mml:math></inline-formula>), while <inline-formula><mml:math id="M42" display="inline"><mml:mi>S</mml:mi></mml:math></inline-formula> is the
semi-perimeter of the same triangle.</p>
      <p id="d1e1005">The variation of length <inline-formula><mml:math id="M43" display="inline"><mml:mi>b</mml:mi></mml:math></inline-formula> corresponds to the contraction of the pneumatic
muscle. This allows for the evaluation, through Eq. (1), of the tensile
force exerted by the PAM at different supply pressures. Finally, the torque
provided by the exoskeleton is obtained.</p>
</sec>
<sec id="Ch1.S2.SS3">
  <label>2.3</label><title>The final cam-based design of the transmission system</title>
      <p id="d1e1023">A second architecture using a cam-based transmission system is also studied.
To avoid the onset of forces that can cause discomfort or undesired
movements of the limb, the cam center must coincide with the ideal center of
the glenohumeral joint (Dehez and Sapin, 2011;
Gull et al., 2020). In addition, the cam should not obstruct the user's
view. To optimize the functionality of the overall architecture, a solution
based on a cam radius increasing with the shoulder elevation angle is
proposed. The tension force produced by the PAM and, consequently, the
shoulder torque provided by the exoskeleton decrease with the contraction
of the PAM. Therefore, the increase in the cam radius should partially
balance the reduction of the maximum tensile force and extend the workspace
of the exoskeleton. The cam design has been performed by the graphical
approach described in detail by Magnetti Gisolo et al. (2021), briefly summarized in the following and shown
in Fig. 4.</p>

      <?xmltex \floatpos{t}?><fig id="Ch1.F4" specific-use="star"><?xmltex \currentcnt{4}?><?xmltex \def\figurename{Figure}?><label>Figure 4</label><caption><p id="d1e1028">Cam profile design obtained by graphical approach: by using
DMSP-20-200N muscle <bold>(a)</bold>, and DMSP-10-100N muscle <bold>(b)</bold>. <bold>(c)</bold> Drawing of cam implementation in the exoskeleton.</p></caption>
          <?xmltex \igopts{width=483.69685pt}?><graphic xlink:href="https://ms.copernicus.org/articles/13/387/2022/ms-13-387-2022-f04.png"/>

        </fig>

      <p id="d1e1046">Previous work (Magnetti Gisolo et al., 2021) showed a
preliminary design of the cam profile, with an initial cam radius <inline-formula><mml:math id="M44" display="inline"><mml:mrow><mml:msub><mml:mi>r</mml:mi><mml:mi mathvariant="normal">i</mml:mi></mml:msub></mml:mrow></mml:math></inline-formula>
equal to 23.5 mm. This solution exhibited good performance; however, it can
be considered only the result of a theoretical optimization approach. For
the actual realization and integration of the cam within the final
exoskeleton design, the initial cam radius should be greater than 34.5 mm,
which represents the longitudinal distance between the acromion (highest
point of the human shoulder complex) and the center of the shoulder
joint (de Leva, 1996). For this reason, the theoretical result
is compared to a more feasible solution that considered an initial cam
radius set equal to 37 mm. By design specification, this value corresponds
to the initial lever arm <inline-formula><mml:math id="M45" display="inline"><mml:mrow><mml:msub><mml:mi>r</mml:mi><mml:mi mathvariant="normal">i</mml:mi></mml:msub></mml:mrow></mml:math></inline-formula> (<inline-formula><mml:math id="M46" display="inline"><mml:mrow><mml:msub><mml:mi mathvariant="italic">θ</mml:mi><mml:mn mathvariant="normal">1</mml:mn></mml:msub><mml:mo>=</mml:mo><mml:mn mathvariant="normal">90</mml:mn><mml:msup><mml:mi/><mml:mo>∘</mml:mo></mml:msup></mml:mrow></mml:math></inline-formula>) of the
muscle force. Starting from this initial condition, the two parameters do
not coincide for any of the higher elevation angles. The initial contraction
of the PAM <inline-formula><mml:math id="M47" display="inline"><mml:mrow><mml:msub><mml:mi>k</mml:mi><mml:mi mathvariant="normal">i</mml:mi></mml:msub></mml:mrow></mml:math></inline-formula> is defined by considering the force–contraction
characteristics for a nominal supply pressure (DMSP-10-100N: 4 bar;
DMSP-20-200N: 2 bar), to balance the gravitational torque calculated at the
initial condition. The behavior of the system is studied for elevation
angles comprised between 90  and 120<inline-formula><mml:math id="M48" display="inline"><mml:msup><mml:mi/><mml:mo>∘</mml:mo></mml:msup></mml:math></inline-formula>. For values
higher than 120<inline-formula><mml:math id="M49" display="inline"><mml:msup><mml:mi/><mml:mo>∘</mml:mo></mml:msup></mml:math></inline-formula>, the PAM reaches the end of its stroke. The
muscle force lever arm at the maximum elevation angle (<inline-formula><mml:math id="M50" display="inline"><mml:mrow><mml:msub><mml:mi>r</mml:mi><mml:mi mathvariant="normal">f</mml:mi></mml:msub></mml:mrow></mml:math></inline-formula>), instead, is
tuned between 40  and 70 mm to achieve the best performance that can be
reached by the PAM selected, given the characteristics shown in Fig. 2. Its
value is selected also by considering that a large <inline-formula><mml:math id="M51" display="inline"><mml:mrow><mml:msub><mml:mi>r</mml:mi><mml:mi mathvariant="normal">f</mml:mi></mml:msub></mml:mrow></mml:math></inline-formula> corresponds to a
large cam radius, likely resulting in a solution hard to implement in the
final structure. The cam profile has been obtained graphically by circular
arc interpolation, ensuring the tangency between the profile itself and the
cable trajectory for the initial and final elevation angles selected. The
iterative process is repeated for two more intermediate positions (<inline-formula><mml:math id="M52" display="inline"><mml:mrow><mml:msub><mml:mi mathvariant="italic">θ</mml:mi><mml:mn mathvariant="normal">1</mml:mn></mml:msub><mml:mo>=</mml:mo><mml:mn mathvariant="normal">100</mml:mn></mml:mrow></mml:math></inline-formula>  and <inline-formula><mml:math id="M53" display="inline"><mml:mrow><mml:msub><mml:mi mathvariant="italic">θ</mml:mi><mml:mn mathvariant="normal">1</mml:mn></mml:msub><mml:mo>=</mml:mo><mml:mn mathvariant="normal">110</mml:mn><mml:msup><mml:mi/><mml:mo>∘</mml:mo></mml:msup></mml:mrow></mml:math></inline-formula>) that are
arbitrarily selected. Finally, discrete data from the CAD files are imported into
MATLAB; then, through a fourth-degree-polynomial interpolation
function, the muscle force lever arm <inline-formula><mml:math id="M54" display="inline"><mml:mi>r</mml:mi></mml:math></inline-formula>, the free cable length <inline-formula><mml:math id="M55" display="inline"><mml:mi>b</mml:mi></mml:math></inline-formula>, and hence the
percentage contraction <inline-formula><mml:math id="M56" display="inline"><mml:mi>k</mml:mi></mml:math></inline-formula> are calculated for each elevation angle within the
working range. Finally, the muscle tension force and the muscle torque are
evaluated, given in Eq. (1), and the analysis of the static equilibrium
condition of the system is performed.</p>
</sec>
<sec id="Ch1.S2.SS4">
  <label>2.4</label><title>Assembly of the exoskeleton including the final cam-based transmission
system</title>
      <p id="d1e1206">A preliminary assembly of the complete exoskeleton is shown in Fig. 5.</p>

      <?xmltex \floatpos{t}?><fig id="Ch1.F5"><?xmltex \currentcnt{5}?><?xmltex \def\figurename{Figure}?><label>Figure 5</label><caption><p id="d1e1211">General structure of the exoskeleton.</p></caption>
          <?xmltex \igopts{width=236.157874pt}?><graphic xlink:href="https://ms.copernicus.org/articles/13/387/2022/ms-13-387-2022-f05.png"/>

        </fig>

      <p id="d1e1220">The PAM (1) is on the user's back. Its upper end is connected to the
structure while the lower end is connected to a cable (2) that is wrapped
around the shoulder pad (3) and connected to the bracelet (4) that supports
the user's upper arm. This bracelet must be rigidly coupled to the structure
of the exoskeleton to prevent sliding along the longitudinal direction of
the arm due to large shear force. Moreover, the position of the bracelet
with respect to the structure of the exoskeleton also depends on the
anthropometry of the user; therefore, a telescopic linear guide (5) could be
used to adjust the longitudinal position of the bracelet along the arm.</p>
      <p id="d1e1224">The human shoulder joint complex can be modeled as a 5 DoF joint: 3 rotations (flexion–extension; abduction–adduction; internal–external
rotation) and 2 translations (elevation–depression and
retraction–protraction). However, the first 2 rotational DoF, with larger
ranges of motion, can be considered the most significant to comfortably
carry out most of the work activities. For this reason, the exoskeleton
architecture proposed integrates a universal joint (6) that replicates
flexion–extension and abduction–adduction of the shoulder. To achieve the
correct functionality, the two rotation axes of the mechanical joint shall
be aligned with the glenohumeral joint axes, and their intersection shall
coincide with the ideal center of such a joint, as shown in Fig. 6. The first
arch of the universal joint is fixed to the frame, while the second one can
rotate with respect to the first one, thanks to a bearing. This relative
motion allows for the shoulder abduction–adduction. Then, a strut connects the
bracelet to the moving arch, and its rotation with respect to the moving
arch matches the flexion–extension of the shoulder joint. The shoulder pad
is rigidly connected to the movable arch of the universal joint so that it
can follow the user's limb during the arm abduction–adduction movement and
limit friction between the cable and the cam profile.</p>

      <?xmltex \floatpos{t}?><fig id="Ch1.F6"><?xmltex \currentcnt{6}?><?xmltex \def\figurename{Figure}?><label>Figure 6</label><caption><p id="d1e1229">Diagram of the universal joint in the frontal plane; SJ
represents the center of the glenohumeral joint.</p></caption>
          <?xmltex \igopts{width=241.848425pt}?><graphic xlink:href="https://ms.copernicus.org/articles/13/387/2022/ms-13-387-2022-f06.png"/>

        </fig>

      <p id="d1e1238">Finally, some adjustable systems are proposed to make the exoskeleton
adaptable to different subjects' physical characteristics:
<list list-type="bullet"><list-item>
      <p id="d1e1243">A telescopic rod (7) is proposed, positioned at the back of the subject, to adjust the
vertical position of the shoulder pad;</p></list-item><list-item>
      <p id="d1e1247">A linear guide (8) is proposed, positioned at the back of the subject, to adjust
horizontally the position of the universal joint with respect to the frame.
To ease this process, the cable must be connected to the lower end of the
actuator through a sheath and two heat clips. In this way, it is not
necessary to align vertically the actuator and the cam;</p></list-item><list-item>
      <p id="d1e1251">A commercial harness (9) is proposed, used to support the rigid structures of the
exoskeleton, allowing us to easily fit the exoskeleton to different
users.</p></list-item></list></p>
</sec>
<sec id="Ch1.S2.SS5">
  <label>2.5</label><title>Simulations</title>
      <p id="d1e1263">Simulations were performed to analyze the two different commercial PAMs and
the two transmission systems presented. The exoskeleton structure was based
on the following geometrical parameters and conditions: <inline-formula><mml:math id="M57" display="inline"><mml:mrow><mml:msub><mml:mi>c</mml:mi><mml:mn mathvariant="normal">0</mml:mn></mml:msub><mml:mo>=</mml:mo><mml:mn mathvariant="normal">0.2</mml:mn></mml:mrow></mml:math></inline-formula> m,
<inline-formula><mml:math id="M58" display="inline"><mml:mrow><mml:mi mathvariant="italic">β</mml:mi><mml:mo>=</mml:mo><mml:mn mathvariant="normal">14</mml:mn></mml:mrow></mml:math></inline-formula>, and <inline-formula><mml:math id="M59" display="inline"><mml:mrow><mml:msub><mml:mi mathvariant="italic">θ</mml:mi><mml:mn mathvariant="normal">2</mml:mn></mml:msub><mml:mo>=</mml:mo><mml:mn mathvariant="normal">0</mml:mn></mml:mrow></mml:math></inline-formula><inline-formula><mml:math id="M60" display="inline"><mml:msup><mml:mi/><mml:mo>∘</mml:mo></mml:msup></mml:math></inline-formula> (see Fig. 3a, b).</p>
      <p id="d1e1316">For the pulley-based design simulations, the constants <inline-formula><mml:math id="M61" display="inline"><mml:mi>a</mml:mi></mml:math></inline-formula> and <inline-formula><mml:math id="M62" display="inline"><mml:mi mathvariant="italic">α</mml:mi></mml:math></inline-formula> (shown
in Fig. 3a) were set equal to 0.15 m and 80<inline-formula><mml:math id="M63" display="inline"><mml:msup><mml:mi/><mml:mo>∘</mml:mo></mml:msup></mml:math></inline-formula>, respectively.
As far as the cam-based design is concerned, the behavior of the device was
tested for both the theoretical optimal value (<inline-formula><mml:math id="M64" display="inline"><mml:mrow><mml:msub><mml:mi>r</mml:mi><mml:mi mathvariant="normal">i</mml:mi></mml:msub><mml:mo>=</mml:mo><mml:mn mathvariant="normal">23.5</mml:mn></mml:mrow></mml:math></inline-formula> mm) and the
actual feasible value selected (<inline-formula><mml:math id="M65" display="inline"><mml:mrow><mml:msub><mml:mi>r</mml:mi><mml:mi mathvariant="normal">i</mml:mi></mml:msub><mml:mo>=</mml:mo><mml:mn mathvariant="normal">37</mml:mn></mml:mrow></mml:math></inline-formula> mm) for the initial cam
radius. The performance of the general system has been evaluated in
different conditions of external load and supply pressure, for several
combinations of shoulder elevation and elbow flexion–extension angles
representative of the theoretical workspace of an exoskeleton for such
applications. In particular, an unloaded condition, considering only the
weight of the arm, and a loaded condition, with an additional 1 kg weight in
the hand, were considered. All the simulations have been performed in the
MATLAB environment.</p>

      <?xmltex \floatpos{t}?><fig id="Ch1.F7" specific-use="star"><?xmltex \currentcnt{7}?><?xmltex \def\figurename{Figure}?><label>Figure 7</label><caption><p id="d1e1374">Gravitational torque in no-load (black line) and 1 kg (dashed
black line), 2 kg (dot-dashed black line), and 3 kg (dotted black line) loaded
conditions as well as torque exerted by the exoskeleton (colored lines) at
different supply pressures, by employing the DMSP-20-200N muscle. The plot
in <bold>(a)</bold> refers to the pulley-based design of the transmission system,
while the plot in <bold>(b)</bold> refers to the cam-based design considering the
theoretical optimal value of <inline-formula><mml:math id="M66" display="inline"><mml:mrow><mml:msub><mml:mi>r</mml:mi><mml:mi mathvariant="normal">i</mml:mi></mml:msub><mml:mo>=</mml:mo><mml:mn mathvariant="normal">23.5</mml:mn></mml:mrow></mml:math></inline-formula> mm.</p></caption>
          <?xmltex \igopts{width=455.244094pt}?><graphic xlink:href="https://ms.copernicus.org/articles/13/387/2022/ms-13-387-2022-f07.png"/>

        </fig>

      <?xmltex \floatpos{t}?><fig id="Ch1.F8"><?xmltex \currentcnt{8}?><?xmltex \def\figurename{Figure}?><label>Figure 8</label><caption><p id="d1e1407">Gravitational torque in no-load (black line) and 1 kg (dashed
black line), 2 kg (dot-dashed black line), and 3 kg (dotted black line) loaded
conditions as well as torque exerted by the exoskeleton at different supply
pressures by employing the DMSP-20-200N muscle and the cam profile with
<inline-formula><mml:math id="M67" display="inline"><mml:mrow><mml:msub><mml:mi>r</mml:mi><mml:mi mathvariant="normal">i</mml:mi></mml:msub><mml:mo>=</mml:mo><mml:mn mathvariant="normal">37</mml:mn></mml:mrow></mml:math></inline-formula> mm.</p></caption>
          <?xmltex \igopts{width=241.848425pt}?><graphic xlink:href="https://ms.copernicus.org/articles/13/387/2022/ms-13-387-2022-f08.png"/>

        </fig>

</sec>
</sec>
<sec id="Ch1.S3">
  <label>3</label><title>Results and discussion</title>
<sec id="Ch1.S3.SS1">
  <label>3.1</label><title>Comparison of FESTO PAMs</title>
      <p id="d1e1447">In the previous study (Magnetti Gisolo et al., 2021), the
DMSP-20-200N pneumatic muscle had been tested in the pulley-based design and
by employing the theoretical optimal value of cam initial radius
(<inline-formula><mml:math id="M68" display="inline"><mml:mrow><mml:msub><mml:mi>r</mml:mi><mml:mi mathvariant="normal">i</mml:mi></mml:msub><mml:mo>=</mml:mo><mml:mn mathvariant="normal">23.5</mml:mn></mml:mrow></mml:math></inline-formula> mm). Figure 7 shows the torque values due to gravity in the unloaded and loaded conditions, along with the torque values exerted by the PAM at
different supply pressures, for both solutions. The limited mismatch between
the gravitational torque and that provided by the exoskeleton suggested that
the cam-based solution can be more effective than the pulley-based design.
In the cam-based solution (Fig. 7b), the exoskeleton provided most of
the muscle work needed to raise the arms and hold the position. The
remaining part, instead, can be easily provided by the user.</p>
      <p id="d1e1465">However, as discussed in Sect. 2.3, the cam with initial radius <inline-formula><mml:math id="M69" display="inline"><mml:mrow><mml:msub><mml:mi>r</mml:mi><mml:mi mathvariant="normal">i</mml:mi></mml:msub></mml:mrow></mml:math></inline-formula> equal
to 23.5 mm cannot be easily mounted over the user's shoulder. For this
reason, the cam profile has been recalculated by increasing the initial
radius. By considering the renewed, feasible cam profile obtained based on
<inline-formula><mml:math id="M70" display="inline"><mml:mrow><mml:msub><mml:mi>r</mml:mi><mml:mi mathvariant="normal">i</mml:mi></mml:msub><mml:mo>=</mml:mo><mml:mn mathvariant="normal">37</mml:mn></mml:mrow></mml:math></inline-formula> mm, the trend of the torque values exerted by the exoskeleton is quite different with respect to the gravitational load (Fig. 8), causing
higher efforts on the shoulder complex muscles to be balanced by the user.
Therefore, the DMSP-20-200N McKibben muscle is not suitable for this
application for any of the transmission systems tested (see Figs. 7a
and  8). The cam-based mechanism (Fig. 8) partially reduces the
mismatch, but the optimal performance could not be achieved due to the cam
size.</p>

      <?xmltex \floatpos{t}?><fig id="Ch1.F9" specific-use="star"><?xmltex \currentcnt{9}?><?xmltex \def\figurename{Figure}?><label>Figure 9</label><caption><p id="d1e1496">Gravitational torque in no-load (black line) and 1 kg (dashed
black line), 2 kg (dot-dashed black line), and 3 kg (dotted black line) loaded
conditions as well as torque exerted by the exoskeleton (colored lines) at
different supply pressures, by employing the DMSP-10-100N muscle. The plot
in <bold>(a)</bold> refers to the pulley-based design of the transmission system,
while the plot in <bold>(b)</bold> refers to the cam-based design considering
<inline-formula><mml:math id="M71" display="inline"><mml:mrow><mml:msub><mml:mi>r</mml:mi><mml:mi mathvariant="normal">i</mml:mi></mml:msub><mml:mo>=</mml:mo><mml:mn mathvariant="normal">37</mml:mn></mml:mrow></mml:math></inline-formula> mm.</p></caption>
          <?xmltex \igopts{width=455.244094pt}?><graphic xlink:href="https://ms.copernicus.org/articles/13/387/2022/ms-13-387-2022-f09.png"/>

        </fig>

      <?xmltex \floatpos{t}?><fig id="Ch1.F10" specific-use="star"><?xmltex \currentcnt{10}?><?xmltex \def\figurename{Figure}?><label>Figure 10</label><caption><p id="d1e1529">Surface of the absolute difference of the torque due to gravity,
with no load, and the torque generated by the DMSP-10-100N PAM, projected on
plane <inline-formula><mml:math id="M72" display="inline"><mml:mi mathvariant="italic">π</mml:mi></mml:math></inline-formula>: <inline-formula><mml:math id="M73" display="inline"><mml:mi mathvariant="normal">Δ</mml:mi></mml:math></inline-formula>Torque <inline-formula><mml:math id="M74" display="inline"><mml:mo>=</mml:mo></mml:math></inline-formula> 0, by employing the shoulder pad at
pressures of 5 <bold>(a)</bold> and 6 bar <bold>(b)</bold>.</p></caption>
          <?xmltex \igopts{width=483.69685pt}?><graphic xlink:href="https://ms.copernicus.org/articles/13/387/2022/ms-13-387-2022-f10.png"/>

        </fig>

      <p id="d1e1565">The adoption of a different PAM (FESTO DMSP-10-100N) highlights a
significant increase in the performance of both transmission systems (Fig. 9). In the unloaded condition, the exoskeleton can balance at least 58 %
of the gravitational torque with the pulley-based design (Fig. 9a),
while the cam-based system provides at least 74 % of the gravitational
torque (Fig. 9b). With respect to the results shown in Fig. 8, the
torque values exerted by the more compact PAM (Fig. 9b) enable a significant reduction of the efforts required by the user to keep the upper limb lifted
in the working position and allow them to obtain the best results among the
tested configurations. As signaled by the curves presented in Fig. 9,
through appropriate regulation of the supply pressure, the device action can
be adapted to the weight of the user's arms and different operating
conditions. On the other hand, the maximum force exerted by the PAM strongly
depends on its size, and even at its maximum operating pressure (8 bar), the
FESTO DMSP-10-100N PAM is not able to fully balance the gravitational torque with
more than 2 kg of additional payload. However, since the proposed
exoskeleton aims to support the user during repetitive lightweight overhead
tasks, the more compact PAM can be considered appropriate for the intended
application.</p>
      <p id="d1e1568">Finally, compared to the FESTO DMSP-20-200N (Fig. 8), higher pressure values
(5 to 6 bar) are required to provide the required traction force and the
corresponding supporting torque at the shoulder when a more compact PAM is
chosen.</p>

      <?xmltex \floatpos{t}?><fig id="Ch1.F11" specific-use="star"><?xmltex \currentcnt{11}?><?xmltex \def\figurename{Figure}?><label>Figure 11</label><caption><p id="d1e1573">Surface of the absolute difference of the torque due to gravity,
in the loaded condition, and the torque generated by the DMSP-10-100N PAM,
projected on plane <inline-formula><mml:math id="M75" display="inline"><mml:mi mathvariant="italic">π</mml:mi></mml:math></inline-formula>: <inline-formula><mml:math id="M76" display="inline"><mml:mi mathvariant="normal">Δ</mml:mi></mml:math></inline-formula>Torque <inline-formula><mml:math id="M77" display="inline"><mml:mo>=</mml:mo></mml:math></inline-formula> 0, by employing the shoulder
pad at pressures of 7 <bold>(a)</bold> and 8 bar <bold>(b)</bold>.</p></caption>
          <?xmltex \igopts{width=483.69685pt}?><graphic xlink:href="https://ms.copernicus.org/articles/13/387/2022/ms-13-387-2022-f11.png"/>

        </fig>

</sec>
<sec id="Ch1.S3.SS2">
  <label>3.2</label><title>Workspace evaluation and discussion for different loading conditions and
supply pressures</title>
      <p id="d1e1617">In this section, the torque provided by the cam-based mechanism, employing
the FESTO DMSP-10-100N actuator, is evaluated by varying both the elevation
angle of the upper arm (<inline-formula><mml:math id="M78" display="inline"><mml:mrow><mml:msub><mml:mi mathvariant="italic">θ</mml:mi><mml:mn mathvariant="normal">1</mml:mn></mml:msub></mml:mrow></mml:math></inline-formula>) and the elbow flexion–extension
angle (<inline-formula><mml:math id="M79" display="inline"><mml:mrow><mml:msub><mml:mi mathvariant="italic">θ</mml:mi><mml:mn mathvariant="normal">2</mml:mn></mml:msub><mml:mo>)</mml:mo></mml:mrow></mml:math></inline-formula>. The ranges selected are <inline-formula><mml:math id="M80" display="inline"><mml:mrow><mml:msub><mml:mi mathvariant="italic">θ</mml:mi><mml:mn mathvariant="normal">1</mml:mn></mml:msub><mml:mo>∈</mml:mo></mml:mrow></mml:math></inline-formula> [90<inline-formula><mml:math id="M81" display="inline"><mml:msup><mml:mi/><mml:mo>∘</mml:mo></mml:msup></mml:math></inline-formula>, 120<inline-formula><mml:math id="M82" display="inline"><mml:msup><mml:mi/><mml:mo>∘</mml:mo></mml:msup></mml:math></inline-formula>], as considered in Sect. 3.1, and <inline-formula><mml:math id="M83" display="inline"><mml:mrow><mml:msub><mml:mi mathvariant="italic">θ</mml:mi><mml:mn mathvariant="normal">2</mml:mn></mml:msub><mml:mo>∈</mml:mo></mml:mrow></mml:math></inline-formula> [0<inline-formula><mml:math id="M84" display="inline"><mml:msup><mml:mi/><mml:mo>∘</mml:mo></mml:msup></mml:math></inline-formula>, 90<inline-formula><mml:math id="M85" display="inline"><mml:msup><mml:mi/><mml:mo>∘</mml:mo></mml:msup></mml:math></inline-formula>], since larger elbow flexion
angles are unlikely maintained during overhead tasks.</p>
      <p id="d1e1707">The absolute difference between the two torque values is calculated for each position inside the theoretical workspace, providing the residual torque
that the shoulder complex muscles must provide to lift or to lower the upper
limb from each equilibrium position. The results of the analysis for the
unloaded condition are shown in Fig. 10 when the DMSP-10-100N pneumatic
muscle is pressurized at 5 bar (Fig. 10a) or 6 bar (Fig. 10b). Those values are
selected given the results of the simulations discussed in Sect. 3.1 (Fig. 9b). The surface <inline-formula><mml:math id="M86" display="inline"><mml:mi mathvariant="normal">Δ</mml:mi></mml:math></inline-formula>Torque, obtained as the absolute
difference between the gravitational torque and the one generated by the
PAM, was projected in a “horizontal” plane <inline-formula><mml:math id="M87" display="inline"><mml:mi mathvariant="italic">π</mml:mi></mml:math></inline-formula>: <inline-formula><mml:math id="M88" display="inline"><mml:mi mathvariant="normal">Δ</mml:mi></mml:math></inline-formula>Torque <inline-formula><mml:math id="M89" display="inline"><mml:mo>=</mml:mo></mml:math></inline-formula> 0.
In Fig. 10a, the black line represents the configuration within the
theoretical workspace that corresponds to the static equilibrium condition,
in which there is no effort on the user's shoulder muscles since the two
torque values are equal. When a supply pressure equal to 6 bar is selected (Fig. 10b), no static equilibrium condition is achieved throughout the workspace, yet no black line is shown. The same result is highlighted in
Fig. 9b, where no intersection between the gravitational torque and
the torque provided by the device is observed for the <inline-formula><mml:math id="M90" display="inline"><mml:mrow><mml:msub><mml:mi mathvariant="italic">θ</mml:mi><mml:mn mathvariant="normal">2</mml:mn></mml:msub><mml:mo>=</mml:mo><mml:mn mathvariant="normal">0</mml:mn></mml:mrow></mml:math></inline-formula> condition. This result confirms the necessity for an appropriate selection
of the supply pressure when a stable equilibrium position is required.
However, due to the limited magnitude of the residual torque shown for most
of the positions inside the workspace (Fig. 10), the worker is expected to
provide such a difference during operation by their muscle strength.</p>
      <p id="d1e1753">Figure 11 reports the effort required from the user in loaded condition by
pressurizing the DMSP-10-100N muscle at higher supply pressures (7 bar, Fig. 11a,
and 8 bar, Fig. 11b). Higher pressures, with respect to the ones selected in
the unloaded condition (see Fig. 10), are required to provide the balancing
torque due to the participation of the additional external load. In both
Figs. 10 and 11, the area surrounding each black line corresponds to low
values of residual torque that are requested from the user to move the arm
away from the equilibrium condition. Especially in the unloaded condition
(Fig. 10), the area corresponding to low values of residual torque (up to
2.5–3 Nm) is large enough to cover the theoretical workspace for the most
part. In this condition, we can assume that the real workspace of the
exoskeleton is rather comparable to the theoretical one. In the loaded
condition (Fig. 11), the workspace seems to be narrower. At such high supply
pressures, even small variations of the PAM tensile force generate large
variations in its length and consequently in the free cable length. Although
the exoskeleton is no longer able to guarantee the desired arm elevation
angle value with the same level of performance obtained in the unloaded
condition, it is still allowed to reach high elevation angles and elbow
flexion–extension angles up to 50<inline-formula><mml:math id="M91" display="inline"><mml:msup><mml:mi/><mml:mo>∘</mml:mo></mml:msup></mml:math></inline-formula>, which might be appropriate for most
of the applications considered.</p>
</sec>
</sec>
<sec id="Ch1.S4" sec-type="conclusions">
  <label>4</label><title>Conclusions</title>
      <p id="d1e1774">In this paper, a novel passive exoskeleton based on McKibben PAMs has been
presented, which aimed at assisting workers during overhead tasks. The use of
pneumatic artificial muscles rather than elastic passive elements has
provided additional flexibility to the solution, given the availability of
these actuators in different sizes, load capabilities, and nonlinear
force–contraction characteristics. Moreover, the intrinsic deformability of
PAMs and their relatively simple use and low cost represent relevant aspects
that may help in the adoption of these devices in such applications.</p>
      <p id="d1e1777">In order to adjust the characteristic of the PAM to the specific
application, i.e., the support of the gravitational load due to raised
arms during work, a specific cam-based design of the transmission system has
been presented. This solution has been discussed and compared to a former
design based on cable and pulley. The cam-based design improves the overall
performance of the exoskeleton by increasing both the effort support and the
upper-limb range of movement. Different commercial PAMs have been also
tested by simulations: in particular, by comparing the results of two FESTO
pneumatic muscles, the DMSP-10-100N model has proven to be the best choice for the
loading conditions tested. The performance of the system has been assessed
for a supply pressure between 0 and 8 bar, delivering an evaluation of the
workspace of the system, in terms of shoulder elevation angle and elbow
flexion–extension angle.</p>
      <p id="d1e1780">Finally, a first assembly of the final exoskeleton has been presented. The
exoskeleton structure must be as lightweight and as simple as possible. In
addition, it must adapt to the user's anthropometric characteristics.
Assuming the use of high-performance mechanical aluminum alloys for the
realization of all structural components, the weight of the exoskeleton is
about 6 kg. The estimated mass is greater than that of commercial passive
upper-limb exoskeletons and could negatively affect the perceived effort of
the lower back and legs. However, this is only a preliminary design. Further
structural analysis will be necessary to optimize the architecture of the
exoskeleton and to choose the most appropriate materials. In addition, a
multibody model could help to study the following: the pressure distribution in the
contact areas between the exoskeleton and the user (e.g., the bracelet), the
motion of the exoskeleton components relative to the body segments, and the
possible alterations to joint angles trajectories. Indeed, all these factors
can cause discomfort and pain for prolonged tasks.</p>
      <p id="d1e1783">The solution presented seems to be promising; however, further work is
necessary to assess the performance of the system in a real scenario. In
particular, the same considerations done for model simulations in the
current work will be verified in the field when a prototype of the system
will be manufactured. In particular, the potential contribution of friction
in the transmission system that was neglected in the simulations might alter
the real force exerted by the PAM, affecting the supporting functionality of
the device. Similarly, pneumatic losses and the exoskeleton weight might
affect the overall behavior. Moreover, to further enhance the short stroke
of the PAM, a cable-based transmission including a reduction system could be
helpful and should be considered in the next versions of the design. A
second parallel passive device could also be considered to increase the
actual workspace of the system.</p>
</sec>

      
      </body>
    <back><notes notes-type="dataavailability"><title>Data availability</title>

      <p id="d1e1791">All data included in this study are available upon request from the
corresponding author.</p>
  </notes><notes notes-type="authorcontribution"><title>Author contributions</title>

      <p id="d1e1797">SMG developed the methodology with contributions by all the co-authors; MP
and CDB contributed to the model simulations and discussion of the results.
MP, SMG, and CDB prepared the original draft; GGM and CF reviewed and edited
the article.</p>
  </notes><notes notes-type="competinginterests"><title>Competing interests</title>

      <p id="d1e1803">The contact author has declared that neither they nor their co-authors have any competing interests.</p>
  </notes><notes notes-type="disclaimer"><title>Disclaimer</title>

      <p id="d1e1809">Publisher’s note: Copernicus Publications remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.</p>
  </notes><notes notes-type="sistatement"><title>Special issue statement</title>

      <p id="d1e1815">This article is part of the special issue “Advances in Service and Industrial Robotics – RAAD2021”. It is a result of the 30th International Conference on Robotics in Alpe-Adria-Danube Region, RAAD 2021, Futuroscope-Poitiers, France, 21–23 June 2021.</p>
  </notes><notes notes-type="reviewstatement"><title>Review statement</title>

      <p id="d1e1821">This paper was edited by Mohamed Amine Laribi and reviewed by Domenico Mundo and one anonymous referee.</p>
  </notes><ref-list>
    <title>References</title>

      <ref id="bib1.bib1"><label>1</label><?label 1?><mixed-citation>Altenburger, R., Scherly, D., and Stadler, K. S.: Design of a passive,
iso-elastic upper limb exoskeleton for gravity compensation, Robomech J.,
3, 1–7, <ext-link xlink:href="https://doi.org/10.1186/s40648-016-0051-5" ext-link-type="DOI">10.1186/s40648-016-0051-5</ext-link>, 2016.</mixed-citation></ref>
      <ref id="bib1.bib2"><label>2</label><?label 1?><mixed-citation>
Angold, R., Lubin, J., Solano, M., Paretich, C., and Mastaler, T.:
Exoskeleton and method of providing an assistive torque to an arm of a
wearer, CA2952403A1, 2017.</mixed-citation></ref>
      <ref id="bib1.bib3"><label>3</label><?label 1?><mixed-citation>Bai, S., Christensen, S., and Islam, M. R. U.: An upper-body exoskeleton with
a novel shoulder mechanism for assistive applications, 2017 IEEE Int. Conf.
Adv. Intell. Mech., 1041–1046, <ext-link xlink:href="https://doi.org/10.1109/AIM.2017.8014156" ext-link-type="DOI">10.1109/AIM.2017.8014156</ext-link>, 2017.</mixed-citation></ref>
      <ref id="bib1.bib4"><label>4</label><?label 1?><mixed-citation>Balasubramanian, S., Wei, H. R., Perez, M., Shepard, B., Koeneman, E.,
Koeneman, J., and He, J.: Rupert: An exoskeleton robot for assisting
rehabilitation of arm functions, in: 2008 Virtual Rehabilitation, IWVR, <ext-link xlink:href="https://doi.org/10.1109/ICVR.2008.4625154" ext-link-type="DOI">10.1109/ICVR.2008.4625154</ext-link>,
163–167, 2008.</mixed-citation></ref>
      <ref id="bib1.bib5"><label>5</label><?label 1?><mixed-citation>Cui, X., Chen, W., Jin, X., and Agrawal, S. K.: Design of a 7-DOF
Cable-Driven Arm Exoskeleton (CAREX-7) and a Controller for Dexterous Motion
Training or Assistance, IEEE/ASME Trans. Mech., 22, 161–172,
<ext-link xlink:href="https://doi.org/10.1109/TMECH.2016.2618888" ext-link-type="DOI">10.1109/TMECH.2016.2618888</ext-link>, 2017.</mixed-citation></ref>
      <ref id="bib1.bib6"><label>6</label><?label 1?><mixed-citation>Dehez, B. and Sapin, J.: ShouldeRO, an alignement-free two-DOF
rehabilitation robot for the shoulder complex, in: 2011 IEEE International
Conference of Rehabilitation Robotics, IEEE, 8 pp., <ext-link xlink:href="https://doi.org/10.1109/ICORR.2011.5975339" ext-link-type="DOI">10.1109/ICORR.2011.5975339</ext-link>, 2011.</mixed-citation></ref>
      <ref id="bib1.bib7"><label>7</label><?label 1?><mixed-citation>de Leva, P.: Adjustments to Zatsiorsky-Seluyanov's segment inertia
parameters, J. Biomech., 29, 1223–1230, <ext-link xlink:href="https://doi.org/10.1002/ima.22019" ext-link-type="DOI">10.1002/ima.22019</ext-link>, 1996.</mixed-citation></ref>
      <ref id="bib1.bib8"><label>8</label><?label 1?><mixed-citation>de Vries, A., Murphy, M., Könemann, R., Kingma, I., and de Looze, M.: The
Amount of Support Provided by a Passive Arm Support Exoskeleton in a Range
of Elevated Arm Postures, IISE Trans. Occup. Ergon. Hum. Factors, 7,
311–321, <ext-link xlink:href="https://doi.org/10.1080/24725838.2019.1669736" ext-link-type="DOI">10.1080/24725838.2019.1669736</ext-link>, 2019.</mixed-citation></ref>
      <ref id="bib1.bib9"><label>9</label><?label 1?><mixed-citation>
Doyle, M. C.: Adaptive arm support systems and methods for use, US20120184880A1, 2013.</mixed-citation></ref>
      <ref id="bib1.bib10"><label>10</label><?label 1?><mixed-citation>Ebrahimi, A.: Stuttgart Exo-Jacket: an Exoskeleton for Industrial Upper Body
Applications, 2017 10th Int. Conf. Hum. Syst. Interact.,  258–263,
<ext-link xlink:href="https://doi.org/10.1109/HSI.2017.8005042" ext-link-type="DOI">10.1109/HSI.2017.8005042</ext-link>, 2017.</mixed-citation></ref>
      <ref id="bib1.bib11"><label>11</label><?label 1?><mixed-citation>Gopura, R. A. R. C. and Kiguchi, K.: Mechanical designs of active upper-limb
exoskeleton robots state-of-the-art and design difficulties, in: 2009 IEEE
International Conference on Rehabilitation Robotics, IEEE, ICORR 2009, <ext-link xlink:href="https://doi.org/10.1109/ICORR.2009.5209630" ext-link-type="DOI">10.1109/ICORR.2009.5209630</ext-link>,
178–187, 2009.</mixed-citation></ref>
      <ref id="bib1.bib12"><label>12</label><?label 1?><mixed-citation>Gull, M. A., Bai, S., and Bak, T.: A review on design of upper limb
exoskeletons, Robotics, 9, 1–35, <ext-link xlink:href="https://doi.org/10.3390/robotics9010016" ext-link-type="DOI">10.3390/robotics9010016</ext-link>, 2020.</mixed-citation></ref>
      <ref id="bib1.bib13"><label>13</label><?label 1?><mixed-citation>
Hall, S. J.: Basic Biomechanics, 6th Edn., edited by: Johonson, C. and
Hash, D. B., McGraw-Hill, New York, 2011.</mixed-citation></ref>
      <ref id="bib1.bib14"><label>14</label><?label 1?><mixed-citation>Kim, S., Nussbaum, M. A., Mokhlespour Esfahani, M. I., Alemi, M. M.,
Alabdulkarim, S., and Rashedi, E.: Assessing the influence of a passive,
upper extremity exoskeletal vest for tasks requiring arm elevation: Part I
– “Expected” effects on discomfort, shoulder muscle activity, and work
task performance, Appl. Ergon., 70, 315–322,
<ext-link xlink:href="https://doi.org/10.1016/j.apergo.2018.02.025" ext-link-type="DOI">10.1016/j.apergo.2018.02.025</ext-link>, 2018.</mixed-citation></ref>
      <ref id="bib1.bib15"><label>15</label><?label 1?><mixed-citation>Klein, J., Spencer, S. J., Allington, J., Minakata, K., Wolbrecht, E. T.,
Smith, R., Bobrow, J. E., and Reinkensmeyer, D. J.: Biomimetic orthosis for
the neurorehabilitation of the elbow and shoulder (BONES), in 2008 2nd
Biennial IEEE RAS &amp; EMBS International Conference on Biomedical Robotics
and Biomechatronics, IEEE, 535–541,  <ext-link xlink:href="https://doi.org/10.1109/BIOROB.2008.4762866" ext-link-type="DOI">10.1109/BIOROB.2008.4762866</ext-link>, 2008.</mixed-citation></ref>
      <ref id="bib1.bib16"><label>16</label><?label 1?><mixed-citation>Lo, H. S. and Xie, S. Q.: Exoskeleton robots for upper-limb rehabilitation:
State of the art and future prospects, Med. Eng. Phys., 34, 261–268,
<ext-link xlink:href="https://doi.org/10.1016/j.medengphy.2011.10.004" ext-link-type="DOI">10.1016/j.medengphy.2011.10.004</ext-link>, 2012.</mixed-citation></ref>
      <ref id="bib1.bib17"><label>17</label><?label 1?><mixed-citation>
Lo Piccolo, M. V., Muscolo, G. G., and Ferraresi, C.: Use of Pneumatic
Artificial Muscles in a Passive Upper Body Exoskeleton, MESROB 2021, in press, 2022.</mixed-citation></ref>
      <ref id="bib1.bib18"><label>18</label><?label 1?><mixed-citation>Magnetti Gisolo, S., Muscolo, G.G., Paterna, M., De Benedictis, C.,
and Ferraresi, C.: Feasibility Study of a Passive Pneumatic Exoskeleton
for Upper Limbs Based on a McKibben Artificial Muscle, in: Advances in Service and Industrial Robotics, edited by:  Zeghloul, S.,
Laribi, M. A., and Sandoval, J.,
RAAD 2021, Mechanisms and Machine Science, Vol. 102, Springer, Cham.,
<ext-link xlink:href="https://doi.org/10.1007/978-3-030-75259-0_23" ext-link-type="DOI">10.1007/978-3-030-75259-0_23</ext-link>, 2021.</mixed-citation></ref>
      <ref id="bib1.bib19"><label>19</label><?label 1?><mixed-citation>Mauri, A., Lettori, J., Fusi, G., Fausti, D., Mor, M., Braghin, F., Legnani,
G., and Roveda, L.: Mechanical and control design of an industrial
exoskeleton for advanced human empowering in heavy parts manipulation tasks,
Robotics, 8, 65, <ext-link xlink:href="https://doi.org/10.3390/robotics8030065" ext-link-type="DOI">10.3390/robotics8030065</ext-link>, 2019.</mixed-citation></ref>
      <ref id="bib1.bib20"><label>20</label><?label 1?><mixed-citation>Maurice, P., Ivaldi, S., Babic, J., Camernik, J., Gorjan, D., Schirrmeister,
B., Bornmann, J., Tagliapietra, L., Latella, C., Pucci, D., and Fritzsche,
L.: Objective and Subjective Effects of a Passive Exoskeleton on Overhead
Work, IEEE Trans. Neural Syst. Rehabil. Eng., 28, 152–164,
<ext-link xlink:href="https://doi.org/10.1109/TNSRE.2019.2945368" ext-link-type="DOI">10.1109/TNSRE.2019.2945368</ext-link>, 2020.</mixed-citation></ref>
      <ref id="bib1.bib21"><label>21</label><?label 1?><mixed-citation>
Moisè, M., Morelli, L., Giovacchini, F., Vitiello, N., and Colombina, G.:
System for assisting an operator in exerting efforts,  WO/2019/016629, 2019.</mixed-citation></ref>
      <ref id="bib1.bib22"><label>22</label><?label 1?><mixed-citation>Otten, B. M., Weidner, R., and Argubi-Wollesen, A.: Evaluation of a Novel
Active Exoskeleton for Tasks at or above Head Level, IEEE Robot. Autom.
Lett., 3, 2408–2415, <ext-link xlink:href="https://doi.org/10.1109/LRA.2018.2812905" ext-link-type="DOI">10.1109/LRA.2018.2812905</ext-link>, 2018.</mixed-citation></ref>
      <ref id="bib1.bib23"><label>23</label><?label 1?><mixed-citation>
Pacifico, I., Scano, A., Guanziroli, E., Moisè, M., Morelli, L.,
Chiavenna, A., Romo, D., Spada, S., Colombina, G., Molteni, F., Giovacchini,
F., Vitiello, N., and Crea, S.: An Experimental Evaluation of the Proto-MATE:
A Novel Ergonomic Upper-Limb Exoskeleton to Reduce Workers' Physical Strain,
IEEE Robot. Autom. Mag., 27, 54–65, 2020.</mixed-citation></ref>
      <ref id="bib1.bib24"><label>24</label><?label 1?><mixed-citation>Pardoel, S. and Doumit, M.: Development and testing of a passive ankle
exoskeleton, Biocybern. Biomed. Eng., 3, 902–913,
<ext-link xlink:href="https://doi.org/10.1016/j.bbe.2019.08.007" ext-link-type="DOI">10.1016/j.bbe.2019.08.007</ext-link>, 2019.</mixed-citation></ref>
      <ref id="bib1.bib25"><label>25</label><?label 1?><mixed-citation>Park, H.-S., Ren, Y., and Zhang, L.-Q.: IntelliArm: an Exoskeleton for
Diagnosis and Treatment of Patients with Neurological Impairments, in: 2008
2nd Biennial IEEE RAS &amp; EMBS International Conference on Biomedical
Robotics and Biomechatronics, IEEE,  109–114, <ext-link xlink:href="https://doi.org/10.1109/BIOROB.2008.4762876" ext-link-type="DOI">10.1109/BIOROB.2008.4762876</ext-link>, 2008.</mixed-citation></ref>
      <ref id="bib1.bib26"><label>26</label><?label 1?><mixed-citation>Pitei, J. and Tóthová, M.: Modelling of pneumatic muscle actuator
using Hill's model with different approximations of static characteristics
of artificial muscle, in: MATEC Web of Conferences,  76,  02015, <ext-link xlink:href="https://doi.org/10.1051/matecconf/20167602015" ext-link-type="DOI">10.1051/matecconf/20167602015</ext-link>, 2016.</mixed-citation></ref>
      <ref id="bib1.bib27"><label>27</label><?label 1?><mixed-citation>Spada, S., Ghibaudo, L., Gilotta, S., Gastaldi, L., and Cavatorta, M. P.:
Investigation into the Applicability of a Passive Upper-limb Exoskeleton in
Automotive Industry, Procedia Manuf., 11, 1255–1262,
<ext-link xlink:href="https://doi.org/10.1016/j.promfg.2017.07.252" ext-link-type="DOI">10.1016/j.promfg.2017.07.252</ext-link>, 2017.</mixed-citation></ref>
      <ref id="bib1.bib28"><label>28</label><?label 1?><mixed-citation>Stadler, K. S., Altenburger, R., Schmidhauser, E., Scherly, D., Ortiz, J.,
Toxiri, S., Mateos, L., and Masood, J.: Robo-mate an exoskeleton for
industrial use – Concept and mechanical design, Adv. Coop. Robot. Proc. 19th
Int. Conf. Climbing Walk. Robot. Support Technol. Mob. Mach. CLAWAR 2016, World Scientific,
806–813, <ext-link xlink:href="https://doi.org/10.1142/9789813149137_0094" ext-link-type="DOI">10.1142/9789813149137_0094</ext-link>, 2016.</mixed-citation></ref>
      <ref id="bib1.bib29"><label>29</label><?label 1?><mixed-citation>Sylla, N., Bonnet, V., Colledani, F., and Fraisse, P.: Ergonomic contribution
of ABLE exoskeleton in automotive industry, Int. J. Ind. Ergon., 44,
475–481, <ext-link xlink:href="https://doi.org/10.1016/j.ergon.2014.03.008" ext-link-type="DOI">10.1016/j.ergon.2014.03.008</ext-link>, 2014.</mixed-citation></ref>
      <ref id="bib1.bib30"><label>30</label><?label 1?><mixed-citation>Tsagarakis, N. G. and Caldwell, D. G.: Development and control of a
“soft-actuated” exoskeleton for use in physiotherapy and training, Auton.
Robots, 15, 21–33, <ext-link xlink:href="https://doi.org/10.1023/A:1024484615192" ext-link-type="DOI">10.1023/A:1024484615192</ext-link>, 2003.</mixed-citation></ref>
      <ref id="bib1.bib31"><label>31</label><?label 1?><mixed-citation>Wang, H.-M., Le, D. K. L., and Lin, W.-C.: Evaluation of a Passive
Upper-Limbs Exoskeleton Applied to Assist Farming Activities in Fruit
Orchards, Appl. Sci., 11, 757, <ext-link xlink:href="https://doi.org/10.3390/app11020757" ext-link-type="DOI">10.3390/app11020757</ext-link>, 2021.</mixed-citation></ref>

  </ref-list></back>
    <!--<article-title-html>A passive upper-limb exoskeleton for industrial application based on pneumatic artificial muscles</article-title-html>
<abstract-html/>
<ref-html id="bib1.bib1"><label>1</label><mixed-citation>
Altenburger, R., Scherly, D., and Stadler, K. S.: Design of a passive,
iso-elastic upper limb exoskeleton for gravity compensation, Robomech J.,
3, 1–7, <a href="https://doi.org/10.1186/s40648-016-0051-5" target="_blank">https://doi.org/10.1186/s40648-016-0051-5</a>, 2016.
</mixed-citation></ref-html>
<ref-html id="bib1.bib2"><label>2</label><mixed-citation>
Angold, R., Lubin, J., Solano, M., Paretich, C., and Mastaler, T.:
Exoskeleton and method of providing an assistive torque to an arm of a
wearer, CA2952403A1, 2017.
</mixed-citation></ref-html>
<ref-html id="bib1.bib3"><label>3</label><mixed-citation>
Bai, S., Christensen, S., and Islam, M. R. U.: An upper-body exoskeleton with
a novel shoulder mechanism for assistive applications, 2017 IEEE Int. Conf.
Adv. Intell. Mech., 1041–1046, <a href="https://doi.org/10.1109/AIM.2017.8014156" target="_blank">https://doi.org/10.1109/AIM.2017.8014156</a>, 2017.
</mixed-citation></ref-html>
<ref-html id="bib1.bib4"><label>4</label><mixed-citation>
Balasubramanian, S., Wei, H. R., Perez, M., Shepard, B., Koeneman, E.,
Koeneman, J., and He, J.: Rupert: An exoskeleton robot for assisting
rehabilitation of arm functions, in: 2008 Virtual Rehabilitation, IWVR, <a href="https://doi.org/10.1109/ICVR.2008.4625154" target="_blank">https://doi.org/10.1109/ICVR.2008.4625154</a>,
163–167, 2008.
</mixed-citation></ref-html>
<ref-html id="bib1.bib5"><label>5</label><mixed-citation>
Cui, X., Chen, W., Jin, X., and Agrawal, S. K.: Design of a 7-DOF
Cable-Driven Arm Exoskeleton (CAREX-7) and a Controller for Dexterous Motion
Training or Assistance, IEEE/ASME Trans. Mech., 22, 161–172,
<a href="https://doi.org/10.1109/TMECH.2016.2618888" target="_blank">https://doi.org/10.1109/TMECH.2016.2618888</a>, 2017.
</mixed-citation></ref-html>
<ref-html id="bib1.bib6"><label>6</label><mixed-citation>
Dehez, B. and Sapin, J.: ShouldeRO, an alignement-free two-DOF
rehabilitation robot for the shoulder complex, in: 2011 IEEE International
Conference of Rehabilitation Robotics, IEEE, 8 pp., <a href="https://doi.org/10.1109/ICORR.2011.5975339" target="_blank">https://doi.org/10.1109/ICORR.2011.5975339</a>, 2011.
</mixed-citation></ref-html>
<ref-html id="bib1.bib7"><label>7</label><mixed-citation>
de Leva, P.: Adjustments to Zatsiorsky-Seluyanov's segment inertia
parameters, J. Biomech., 29, 1223–1230, <a href="https://doi.org/10.1002/ima.22019" target="_blank">https://doi.org/10.1002/ima.22019</a>, 1996.
</mixed-citation></ref-html>
<ref-html id="bib1.bib8"><label>8</label><mixed-citation>
de Vries, A., Murphy, M., Könemann, R., Kingma, I., and de Looze, M.: The
Amount of Support Provided by a Passive Arm Support Exoskeleton in a Range
of Elevated Arm Postures, IISE Trans. Occup. Ergon. Hum. Factors, 7,
311–321, <a href="https://doi.org/10.1080/24725838.2019.1669736" target="_blank">https://doi.org/10.1080/24725838.2019.1669736</a>, 2019.
</mixed-citation></ref-html>
<ref-html id="bib1.bib9"><label>9</label><mixed-citation>
Doyle, M. C.: Adaptive arm support systems and methods for use, US20120184880A1, 2013.
</mixed-citation></ref-html>
<ref-html id="bib1.bib10"><label>10</label><mixed-citation>
Ebrahimi, A.: Stuttgart Exo-Jacket: an Exoskeleton for Industrial Upper Body
Applications, 2017 10th Int. Conf. Hum. Syst. Interact.,  258–263,
<a href="https://doi.org/10.1109/HSI.2017.8005042" target="_blank">https://doi.org/10.1109/HSI.2017.8005042</a>, 2017.
</mixed-citation></ref-html>
<ref-html id="bib1.bib11"><label>11</label><mixed-citation>
Gopura, R. A. R. C. and Kiguchi, K.: Mechanical designs of active upper-limb
exoskeleton robots state-of-the-art and design difficulties, in: 2009 IEEE
International Conference on Rehabilitation Robotics, IEEE, ICORR 2009, <a href="https://doi.org/10.1109/ICORR.2009.5209630" target="_blank">https://doi.org/10.1109/ICORR.2009.5209630</a>,
178–187, 2009.
</mixed-citation></ref-html>
<ref-html id="bib1.bib12"><label>12</label><mixed-citation>
Gull, M. A., Bai, S., and Bak, T.: A review on design of upper limb
exoskeletons, Robotics, 9, 1–35, <a href="https://doi.org/10.3390/robotics9010016" target="_blank">https://doi.org/10.3390/robotics9010016</a>, 2020.
</mixed-citation></ref-html>
<ref-html id="bib1.bib13"><label>13</label><mixed-citation>
Hall, S. J.: Basic Biomechanics, 6th Edn., edited by: Johonson, C. and
Hash, D. B., McGraw-Hill, New York, 2011.
</mixed-citation></ref-html>
<ref-html id="bib1.bib14"><label>14</label><mixed-citation>
Kim, S., Nussbaum, M. A., Mokhlespour Esfahani, M. I., Alemi, M. M.,
Alabdulkarim, S., and Rashedi, E.: Assessing the influence of a passive,
upper extremity exoskeletal vest for tasks requiring arm elevation: Part I
– “Expected” effects on discomfort, shoulder muscle activity, and work
task performance, Appl. Ergon., 70, 315–322,
<a href="https://doi.org/10.1016/j.apergo.2018.02.025" target="_blank">https://doi.org/10.1016/j.apergo.2018.02.025</a>, 2018.
</mixed-citation></ref-html>
<ref-html id="bib1.bib15"><label>15</label><mixed-citation>
Klein, J., Spencer, S. J., Allington, J., Minakata, K., Wolbrecht, E. T.,
Smith, R., Bobrow, J. E., and Reinkensmeyer, D. J.: Biomimetic orthosis for
the neurorehabilitation of the elbow and shoulder (BONES), in 2008 2nd
Biennial IEEE RAS &amp; EMBS International Conference on Biomedical Robotics
and Biomechatronics, IEEE, 535–541,  <a href="https://doi.org/10.1109/BIOROB.2008.4762866" target="_blank">https://doi.org/10.1109/BIOROB.2008.4762866</a>, 2008.
</mixed-citation></ref-html>
<ref-html id="bib1.bib16"><label>16</label><mixed-citation>
Lo, H. S. and Xie, S. Q.: Exoskeleton robots for upper-limb rehabilitation:
State of the art and future prospects, Med. Eng. Phys., 34, 261–268,
<a href="https://doi.org/10.1016/j.medengphy.2011.10.004" target="_blank">https://doi.org/10.1016/j.medengphy.2011.10.004</a>, 2012.
</mixed-citation></ref-html>
<ref-html id="bib1.bib17"><label>17</label><mixed-citation>
Lo Piccolo, M. V., Muscolo, G. G., and Ferraresi, C.: Use of Pneumatic
Artificial Muscles in a Passive Upper Body Exoskeleton, MESROB 2021, in press, 2022.
</mixed-citation></ref-html>
<ref-html id="bib1.bib18"><label>18</label><mixed-citation>
Magnetti Gisolo, S., Muscolo, G.G., Paterna, M., De Benedictis, C.,
and Ferraresi, C.: Feasibility Study of a Passive Pneumatic Exoskeleton
for Upper Limbs Based on a McKibben Artificial Muscle, in: Advances in Service and Industrial Robotics, edited by:  Zeghloul, S.,
Laribi, M. A., and Sandoval, J.,
RAAD 2021, Mechanisms and Machine Science, Vol. 102, Springer, Cham.,
<a href="https://doi.org/10.1007/978-3-030-75259-0_23" target="_blank">https://doi.org/10.1007/978-3-030-75259-0_23</a>, 2021.
</mixed-citation></ref-html>
<ref-html id="bib1.bib19"><label>19</label><mixed-citation>
Mauri, A., Lettori, J., Fusi, G., Fausti, D., Mor, M., Braghin, F., Legnani,
G., and Roveda, L.: Mechanical and control design of an industrial
exoskeleton for advanced human empowering in heavy parts manipulation tasks,
Robotics, 8, 65, <a href="https://doi.org/10.3390/robotics8030065" target="_blank">https://doi.org/10.3390/robotics8030065</a>, 2019.
</mixed-citation></ref-html>
<ref-html id="bib1.bib20"><label>20</label><mixed-citation>
Maurice, P., Ivaldi, S., Babic, J., Camernik, J., Gorjan, D., Schirrmeister,
B., Bornmann, J., Tagliapietra, L., Latella, C., Pucci, D., and Fritzsche,
L.: Objective and Subjective Effects of a Passive Exoskeleton on Overhead
Work, IEEE Trans. Neural Syst. Rehabil. Eng., 28, 152–164,
<a href="https://doi.org/10.1109/TNSRE.2019.2945368" target="_blank">https://doi.org/10.1109/TNSRE.2019.2945368</a>, 2020.
</mixed-citation></ref-html>
<ref-html id="bib1.bib21"><label>21</label><mixed-citation>
Moisè, M., Morelli, L., Giovacchini, F., Vitiello, N., and Colombina, G.:
System for assisting an operator in exerting efforts,  WO/2019/016629, 2019.
</mixed-citation></ref-html>
<ref-html id="bib1.bib22"><label>22</label><mixed-citation>
Otten, B. M., Weidner, R., and Argubi-Wollesen, A.: Evaluation of a Novel
Active Exoskeleton for Tasks at or above Head Level, IEEE Robot. Autom.
Lett., 3, 2408–2415, <a href="https://doi.org/10.1109/LRA.2018.2812905" target="_blank">https://doi.org/10.1109/LRA.2018.2812905</a>, 2018.
</mixed-citation></ref-html>
<ref-html id="bib1.bib23"><label>23</label><mixed-citation>
Pacifico, I., Scano, A., Guanziroli, E., Moisè, M., Morelli, L.,
Chiavenna, A., Romo, D., Spada, S., Colombina, G., Molteni, F., Giovacchini,
F., Vitiello, N., and Crea, S.: An Experimental Evaluation of the Proto-MATE:
A Novel Ergonomic Upper-Limb Exoskeleton to Reduce Workers' Physical Strain,
IEEE Robot. Autom. Mag., 27, 54–65, 2020.
</mixed-citation></ref-html>
<ref-html id="bib1.bib24"><label>24</label><mixed-citation>
Pardoel, S. and Doumit, M.: Development and testing of a passive ankle
exoskeleton, Biocybern. Biomed. Eng., 3, 902–913,
<a href="https://doi.org/10.1016/j.bbe.2019.08.007" target="_blank">https://doi.org/10.1016/j.bbe.2019.08.007</a>, 2019.
</mixed-citation></ref-html>
<ref-html id="bib1.bib25"><label>25</label><mixed-citation>
Park, H.-S., Ren, Y., and Zhang, L.-Q.: IntelliArm: an Exoskeleton for
Diagnosis and Treatment of Patients with Neurological Impairments, in: 2008
2nd Biennial IEEE RAS &amp; EMBS International Conference on Biomedical
Robotics and Biomechatronics, IEEE,  109–114, <a href="https://doi.org/10.1109/BIOROB.2008.4762876" target="_blank">https://doi.org/10.1109/BIOROB.2008.4762876</a>, 2008.
</mixed-citation></ref-html>
<ref-html id="bib1.bib26"><label>26</label><mixed-citation>
Pitei, J. and Tóthová, M.: Modelling of pneumatic muscle actuator
using Hill's model with different approximations of static characteristics
of artificial muscle, in: MATEC Web of Conferences,  76,  02015, <a href="https://doi.org/10.1051/matecconf/20167602015" target="_blank">https://doi.org/10.1051/matecconf/20167602015</a>, 2016.
</mixed-citation></ref-html>
<ref-html id="bib1.bib27"><label>27</label><mixed-citation>
Spada, S., Ghibaudo, L., Gilotta, S., Gastaldi, L., and Cavatorta, M. P.:
Investigation into the Applicability of a Passive Upper-limb Exoskeleton in
Automotive Industry, Procedia Manuf., 11, 1255–1262,
<a href="https://doi.org/10.1016/j.promfg.2017.07.252" target="_blank">https://doi.org/10.1016/j.promfg.2017.07.252</a>, 2017.
</mixed-citation></ref-html>
<ref-html id="bib1.bib28"><label>28</label><mixed-citation>
Stadler, K. S., Altenburger, R., Schmidhauser, E., Scherly, D., Ortiz, J.,
Toxiri, S., Mateos, L., and Masood, J.: Robo-mate an exoskeleton for
industrial use – Concept and mechanical design, Adv. Coop. Robot. Proc. 19th
Int. Conf. Climbing Walk. Robot. Support Technol. Mob. Mach. CLAWAR 2016, World Scientific,
806–813, <a href="https://doi.org/10.1142/9789813149137_0094" target="_blank">https://doi.org/10.1142/9789813149137_0094</a>, 2016.
</mixed-citation></ref-html>
<ref-html id="bib1.bib29"><label>29</label><mixed-citation>
Sylla, N., Bonnet, V., Colledani, F., and Fraisse, P.: Ergonomic contribution
of ABLE exoskeleton in automotive industry, Int. J. Ind. Ergon., 44,
475–481, <a href="https://doi.org/10.1016/j.ergon.2014.03.008" target="_blank">https://doi.org/10.1016/j.ergon.2014.03.008</a>, 2014.
</mixed-citation></ref-html>
<ref-html id="bib1.bib30"><label>30</label><mixed-citation>
Tsagarakis, N. G. and Caldwell, D. G.: Development and control of a
“soft-actuated” exoskeleton for use in physiotherapy and training, Auton.
Robots, 15, 21–33, <a href="https://doi.org/10.1023/A:1024484615192" target="_blank">https://doi.org/10.1023/A:1024484615192</a>, 2003.
</mixed-citation></ref-html>
<ref-html id="bib1.bib31"><label>31</label><mixed-citation>
Wang, H.-M., Le, D. K. L., and Lin, W.-C.: Evaluation of a Passive
Upper-Limbs Exoskeleton Applied to Assist Farming Activities in Fruit
Orchards, Appl. Sci., 11, 757, <a href="https://doi.org/10.3390/app11020757" target="_blank">https://doi.org/10.3390/app11020757</a>, 2021.
</mixed-citation></ref-html>--></article>
